Lots of good opinions/advice here. I went with a 30.06 due to the variety and availability of ammunition. My rifle is a Savage 116 with a stainless barrel and a 3x9-40 Nikon scope. For mule deer I am shooting the 160 grain Winchester Power Max ammunition. I also considered this rifle in a 7mm-08 but decided against it. The ammo costs more and I wanted to be able to buy ammo in pretty any small town hardware store since I am not loading my own.