I have been running solo shuttles on my bike since fishing opened back up. I will usually drop the boat at the put-in, move it away from the launch / hide it as much as possible (with no gear in it), drive truck and trailer to takeout, throw all my gear including waders and boots in a backpack with rod tube strapped to it, and use anxiety about my boat getting messed with or stolen to fuel a fast pedal back. Last time, I did leave my waders and boots hidden in the boat so I didn't have to bike with them.
Jan 2019 I did a month of bike touring, camping, and fly fishing through Chilean Patagonia. Fit two rods off the back strapped to a back rack. Made the bike long but had no issues with it and no leg rub associated with trying to have it along the top tube or down tube. Eventually started packing my sleeping bag in my waders, strapped to handlebars, as a makeshift dry bag.
Did some biking in waders and boots....it worked and would work moving spot to spot...but wasn't ideal obviously.
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Use Crank Bros. double shots on my bike - they're awesome and wouldn't trade them for anything.
Ryder