Actually, a mRNA vaccine has the information to make a viral spike protei. It does not contain the viral spike protein itself. The lipid coating facilitates penetration of the mRNA through the cell membrane of immune cells. Once inside, the normal cell machinery (ribosomes -> endoplasmic reticulum -> Golgi apparatus) synthesize the spike protein from the mRNA. All cells "post" a subsample of their synthesized proteins via MHC class I proteins to the surface of their cell membranes where they are "visible" to other immune cells. When a subset of the other immune cells encounter these foreign proteins, they are spurred to activate (attack) and to divide (create more cells that are sensitive to the same protein).I would never recommend making healthcare decisions based on a fishing forum. We fisherman are prone to exaggeration and independent spirit. However.
This is a very watered down explanation of determining reaction versus immune response. The Atlantic has done a fantastic job of covering COVID-19.
Highly recommend this read.
Side effects are just a sign that protection is kicking in as it should.www.theatlantic.com
While it has been addressed multiple times over in this thread, differentiating between a “reaction” and an individuals immune response is very important.
An individuals immune response is unique, complex and not necessarily an indicator of neither a vaccines efficacy or perceived deficiency.
A very basic explanation of mRNA vaccines (explained several ways in this thread) is a non-active viral spike protein encapsulated in a lipid (virus dna in fat) is injected into deep muscle tissue. The body absorbs the “fat” and creates a healthy “response.”
The localized inflammation in the arm or “pain” is a by product of the body detecting the lipid as a foreign body and the spike protein as “bad”.
Shot 1 primes the immune system to develop a “response.”
Shot 2 reintroduces the same fat and genetic material. Our immune system detects it and starts to freak out in that it saw this once before and thought it had developed a response.
There is a basic saying in medicine. When you hear hoof beats, think of horses. Not zebras. Meaning, exotic “alternative” theories are just that, exotic.
Unfortunately, the scientific method, a process that takes time, is under the microscope of social media, 24 hour news and sound bites.
Please do get vaccinated. Do not let the virus use your body as a lab for developing variants.
We are all in a unique period of history. How we respond as a community, as a group of individuals blessed by the hard work and sacrifice of generations before us, will dictate the record book. Not political affiliation.
The Atlantic article also does a good job of explaining the localized effects of the innate immune system that may be triggered by the lipid coating or even the mRNA itself.