So money is no object but what about time? As you get older time is your daily friend, or not in most cases.
Do what you can when you can and forget the cost! If you can pay your bills and have food on the table and a roof over your head and maybe a significant other to share your space and is into what you are doing then go fish.
Tough choice between the Seychelles and Isla Secas Panama. Unlikely that I could ever afford it but since we're fantasizing I'd lean towards Panama. No guilt leaving the wife in the lap of luxury while I'm out getting my ass kicked by giant yellowfin tuna, huge dogtooth snapper, and many other big mean fish that would have me seeking spa services at the end of the day.